4-Chloro-2-(Trifluoroacetyl)aniline Hydrochloride is a pharmaceutical intermediate featuring both chloro and trifluoroacetyl groups attached to an aniline ring. This compound is used in the synthesis of biologically active molecules, particularly in the development of drugs with targeted therapeutic applications. The trifluoroacetyl group confers important reactivity to the molecule, allowing for selective transformations and enhancing its stability in various chemical reactions.
This intermediate is essential in the production of more complex molecules used in medicinal chemistry and drug design, as well as in the synthesis of agrochemical compounds.
| Property | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | ≥98% |
| CAS Number | 173676-59-0 |
| Molecular Formula | C8H7ClF3NO·HCl |
| Solubility | Soluble in organic solvents (e.g., ethanol) |
| Storage Conditions | Store in a cool, dry place, away from moisture and heat |
| Packaging | Available in 25 kg, 50 kg, or 200 kg drums, or customized packaging options |
Pharmaceutical Synthesis:
4-Chloro-2-(Trifluoroacetyl)aniline Hydrochloride plays a significant role in the synthesis of active pharmaceutical ingredients (APIs), particularly those involved in neurological, anticancer, and anti-inflammatory treatments. It serves as a key intermediate in the formation of various biologically active molecules.
Organic Synthesis:
The compound is widely used as a building block in the preparation of other complex organic molecules, especially in the development of trifluoromethylated compounds and other fluorine-containing chemicals that are important for pharmaceuticals and agrochemicals.
Agrochemical Applications:
It can also be employed in the production of agrochemicals, including pesticides, fungicides, and herbicides.
Storage:
Store in a cool, dry, and well-ventilated area. Keep the container tightly sealed when not in use. Avoid exposure to moisture, heat, and direct sunlight to ensure product stability.
Shelf Life:
The product has a shelf life of 2 years when stored under recommended conditions.
Handling:
When handling this chemical, wear appropriate personal protective equipment (PPE), such as gloves, goggles, and a lab coat. Ensure good ventilation to avoid inhalation of any fumes. Always follow safety procedures for handling hazardous chemicals.
Safety:
In case of skin or eye contact, rinse immediately with plenty of water. If inhaled, move the affected individual to fresh air and seek medical attention if necessary. Use in a well-ventilated area.
Environmental Impact:
Dispose of the product according to local regulations. Avoid discharge into waterways. Proper waste disposal procedures must be followed to minimize environmental impact.
