4-(2-Isopropylaminoethyl)-1,3-Dichloro-2H-Indol-2-One Hydrochloride (Ropinirole Hydrochloride) is a key pharmaceutical intermediate primarily used in the synthesis of Ropinirole, a medication used for the treatment of Parkinson's disease and restless leg syndrome. This compound is a dopamine agonist that selectively activates dopamine D2 and D3 receptors in the brain, which helps in managing symptoms associated with these conditions.
It serves as an essential building block in the synthesis of Ropinirole, enabling the production of the therapeutic agent used to restore motor function in patients.
| Property | Specification |
|---|---|
| Appearance | White or off-white powder |
| Purity | ≥99.0% (HPLC) |
| CAS Number | 91374-20-8 |
| Molecular Formula | C16H21Cl2N3O |
| Melting Point | 224-226°C |
| Solubility | Soluble in water, methanol, and ethanol |
| Storage Conditions | Store in a cool, dry place, away from light and moisture |
| Packaging | Available in 25 kg, 50 kg, or 200 kg drums or customized packaging options |
Pharmaceutical Synthesis:
Ropinirole Hydrochloride is a vital intermediate in the production of Ropinirole, which is commonly prescribed for the treatment of Parkinson's disease and restless leg syndrome. Its role in stimulating dopamine receptors helps improve motor function in patients with neurological disorders.
Chemical Synthesis:
This compound can be used as a building block for other biologically active compounds, contributing to the synthesis of novel therapeutic agents.
Storage:
Store in a cool, dry place away from direct sunlight and moisture. Keep the container tightly sealed when not in use to maintain product integrity.
Shelf Life:
The product has a shelf life of 2 years when stored under appropriate conditions.
Handling:
Always wear appropriate personal protective equipment (PPE), such as gloves, goggles, and a lab coat, when handling this material. Ensure adequate ventilation in the working area.
Safety:
In case of skin or eye contact, flush immediately with water. If inhaled, move to fresh air and seek medical attention if necessary.
Environmental Impact:
Dispose of the product following local regulations. Avoid releasing the compound into water sources or the environment.
