2,3,5,6-Tetrafluoropyridine Pharmaceutical Intermediates | CAS 460-45-3 | Ideal for Chemical Reactions
Product Name: 2,3,5,6-Tetrafluoropyridine
CAS Number: 2875-18-5
Molecular Formula: C5H2F4N
Purity: ≥98.0%
Appearance: Colorless to pale yellow liquid or solid
Packaging: Available in 25 kg, 50 kg, or 200 kg plastic drums or customized packaging upon request.
2,3,5,6-Tetrafluoropyridine is a high-purity pharmaceutical intermediate widely used in the synthesis of fluorinated organic compounds. With a purity of ≥98%, this compound is characterized by four fluorine atoms attached to the pyridine ring, which imparts unique properties such as enhanced chemical stability and reactivity. This makes it an essential building block in the synthesis of fluorine-containing pharmaceuticals, pesticides, and other fluorinated chemicals.
The compound is colorless to pale yellow and can exist in either a liquid or solid form, depending on the conditions. It is primarily used in the preparation of fluorinated derivatives that are of interest in drug discovery, catalysis, and chemical manufacturing.
| Property | Specification |
|---|---|
| Appearance | Colorless to pale yellow liquid or solid |
| Purity | ≥98.0% |
| CAS Number | 2875-18-5 |
| Molecular Formula | C5H2F4N |
| Melting Point | 3-5°C |
| Boiling Point | 127°C (approx.) |
| Solubility | Soluble in organic solvents like ethanol, DMSO; insoluble in water |
| Odor | Slight characteristic odor |
Pharmaceutical Synthesis: 2,3,5,6-Tetrafluoropyridine is widely used in the fluorination of pyridine derivatives, which are important intermediates in the development of antiviral, antibiotic, and anticancer drugs. The incorporation of fluorine atoms enhances the stability and bioactivity of the resulting compounds.
Fluorine-Containing Chemical Synthesis: This compound is an essential precursor for the synthesis of fluorinated agrochemicals, pesticides, and other fluorinated organic compounds.
Catalyst Development: Due to its fluorine-substituted pyridine structure, 2,3,5,6-Tetrafluoropyridine is used in the development of fluorinated catalysts that exhibit high performance in various chemical reactions.
Research and Development: It is a key intermediate for the synthesis of specialty fluorinated materials, including those used in the development of fluorine-based polymers and other advanced materials in chemical research.
Storage Conditions: Store in a cool, dry place, away from heat and direct sunlight. Keep containers tightly sealed to prevent moisture and contamination.
Shelf Life: The compound remains stable for up to 2 years if stored properly under recommended conditions.
Handling: Use appropriate protective equipment, including gloves, goggles, and a lab coat when handling. Ensure adequate ventilation when working with the compound in bulk or when preparing solutions.
Safety: 2,3,5,6-Tetrafluoropyridine is considered to have low toxicity, but may cause irritation to the eyes and skin. It is important to follow the Material Safety Data Sheet (MSDS) when handling the product.
Environmental Impact: The compound is not considered highly toxic to the environment; however, it should be handled with care to prevent contamination of water systems. Follow proper disposal procedures as per local regulations.
