5-Bromo-2-Cyano-3-Nitropyridine Pharmaceutical Intermediate Purity ≥98% for High-Quality Synthesis
Product Name: 5-Bromo-2-Cyano-3-Nitropyridine
CAS Number: 573675-25-9
Molecular Formula: C6H2BrN3O2
Purity: ≥98%
Appearance: Off-white to pale yellow crystalline powder
Packaging: Available in 25 kg, 50 kg, or 200 kg plastic drums or customized packaging upon request.
5-Bromo-2-Cyano-3-Nitropyridine is a high-purity pharmaceutical intermediate primarily used in the synthesis of various bioactive compounds. This compound has a purity of ≥98% and is typically a pale yellow to off-white crystalline powder. Due to its structure, it serves as a valuable building block for the synthesis of pyridine-based pharmaceuticals, including antibiotics, anticancer drugs, and other biologically active molecules.
The bromo, cyano, and nitro functional groups make it a versatile intermediate for chemical reactions, particularly for cross-coupling reactions and other transformations to obtain specialized pyridine derivatives with potential therapeutic applications.
| Property | Specification |
|---|---|
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | ≥98% |
| CAS Number | 573675-25-9 |
| Molecular Formula | C6H2BrN3O2 |
| Melting Point | 168-172°C |
| Boiling Point | 400°C (approx.) |
| Solubility | Soluble in organic solvents (e.g., DMSO), slightly soluble in water |
| Odor | Odorless or faint characteristic odor |
Pharmaceutical Synthesis: 5-Bromo-2-Cyano-3-Nitropyridine is widely used as an intermediate for the synthesis of pharmaceutical compounds. It is especially important in the production of antitumor, antimicrobial, and anti-inflammatory drugs.
Organic Synthesis: The compound is a building block for the synthesis of functionalized pyridine derivatives. The bromine, cyano, and nitro groups offer reactivity that is useful in several organic transformations, including nucleophilic substitution and cross-coupling reactions.
Agrochemical Synthesis: This intermediate can be utilized in the synthesis of agrochemicals and pesticides, contributing to the development of effective chemical formulations.
Chemical Research: 5-Bromo-2-Cyano-3-Nitropyridine is valuable in chemical research and the development of specialty chemicals and chiral intermediates used in industrial and pharmaceutical applications.
Storage Conditions: Store in a cool, dry place away from heat, direct sunlight, and moisture. Ensure containers are tightly sealed to prevent contamination.
Shelf Life: When stored under recommended conditions, 5-Bromo-2-Cyano-3-Nitropyridine has a shelf life of 2 years from the date of manufacture.
Handling: Use protective equipment such as gloves, safety goggles, and a lab coat when handling this compound. Work in a well-ventilated area, especially when handling large quantities or when preparing solutions.
Safety: This compound may cause skin and eye irritation. If contact occurs, flush the affected area with water and seek medical attention if necessary. Always follow Material Safety Data Sheet (MSDS) guidelines for handling.
Environmental Impact: 5-Bromo-2-Cyano-3-Nitropyridine may be harmful to aquatic life. Do not dispose of the product into waterways. Follow local regulations for disposal and recycling of chemicals to minimize environmental impact.
